AC Milan and Inter Milan go head-to-head in not just the Derby della Madonnina, but also the Scudetto showdown.

This is the biggest game of the season, as new leaders Inter start Christian Eriksen with Romelu Lukaku against a Milan side one point behind using Zlatan Ibrahimovic and Hakan Calhanoglu.

The Nerazzurri leapfrogged the Rossoneri last week, so Antonio Conte’s men could break away or lose the top spot already.

Inter miss only Stefano Sensi with another muscular issue, but Arturo Vidal isn’t ready to start after a knock to the knee that also ruled him out of last week’s 3-1 win over Lazio.

Christian Eriksen therefore gets the nod in midfield with Marcelo Brozovic and Nicolò Barella, while Achraf Hakimi and Ivan Perisic take the wings.

Lautaro Martinez stands by Romelu Lukaku, the Belgian centre-forward having scored in his last three Serie A editions of the Derby della Madonnina.

He also found the net – and clashed with Ibrahimovic – in the Coppa Italia quarter-final last month, when Inter won 2-1 in stoppages through an Eriksen free kick after Zlatan had been sent off.

This is the first time the Milan Derby has been played with both clubs in the top two since April 2011.

The Rossoneri won 3-0 that time and went on to celebrate their most recent Scudetto.

AC Milan: G Donnarumma; Calabria, Kjaer, Romagnoli, Theo Hernandez; Tonali, Kessie; Saelemaekers, Calhanoglu, Rebic; Ibrahimovic

AC Milan Bench: Tatarusanu, A Donnarumma, Dalot, Castillejo, Hauge, Meite, Leao, Kalulu, Brahim Diaz, Tomori, Krunic, Gabbia

Inter Milan: Handanovic; Skriniar, De Vrij, Bastoni; Hakimi, Barella, Brozovic, Eriksen, Perisic; Lautaro Martinez, Lukaku

Inter Bench: Padelli, Radu; Darmian, Kolarov, D’Ambrosio, Ranocchia; Gagliardini, Vecino, Vidal, Young; Pinamonti, Sanchez

Ref: Doveri